At first I could not get used to the tabs being on top of the browser. This is a purely stylistic thing since I was used to Firefox and its tab location. Chrome gives you something that other browsers do not have - you can drag a single tab away from the others making it a separate window. You can also rearrange the tabs by putting them where you want them. This allows you to have a number of sites next to each other to simplify tasks such as comparing prices.
There are other features which I have yet to discover. But restoring the previously opened tabs upon start up is one feature I happily enabled. I used it rather heavily in Firefox and shutting down my PC without it would have proved somewhat difficult.